Scaffold Fixation and Distensibility Device (FADD)

Scaffold Fixation and Distensibility Device (FADD)


Sam Bonfig



Cheryl Miller, Ph.D.

Roobik Gharabagi, Ph.D.

Kyle Mitchell, Ph.D.

For the most up-to-date information, visit the students project website.  

Project Overview

The use of synthetic scaffolds to simulate tissue and provide a cell medium has become an industry standard in both neuroscience and tissue engineering applications.  This proposal is for the designing, testing, and implementation of a scaffold fixation and distensibility device.  While synthetic scaffolds have undoubtedly expanded the field of applicable medical research, they are very small, fragile, and electrostatically charged, making them difficult to handle amongst standard laboratory equipment.  The primary benefit of a scaffold fixation and distensibility device is to provide a means to reliably quantify scaffold length, stretch, and elasticity.  Additionally, a scaffold fixation and distensibility device that would work with a multitude of scaffold types (sizes, compositions, maturations, etc.) would broaden the horizon for cell-seeded scaffold stretch studies to be accurately conducted.

Project functions include an initial assessment of material properties to optimize biocompatibility and a design phase to develop a prototype that will allow for precise, consistent scaffold stretch to various degrees.  Data analysis and device assessment can be considered additional functions in light of design improvements.  Relevant skills for this project include biomaterials, neuroscience, physiology, mechanics, numerical analysis, and hardware/tooling abilities.  Given the skill-set required to complete this project, a team of one BME will be sufficient.