Elastin Contribution to Bone Properties

Elastin Contribution to Bone Properties

Student(s):

Benjamen O’Donnell, Biomedical Engineering

Advisor(s):

Gary Bledsoe, Ph.D., Chair and Professor of Biomedical Engineering

A 3-Pt. bending test is a common flexural test method for the determining several properties of a material, most notably the ultimate strength, ultimate stress, elastic modulus (young’s modulus), and yield strength. A common problem with using a 3-Pt. bending test on biological materials is that their shape is often difficult to work with. Mice femurs have a curve in the shaft, which causes them to roll when put under load in a 3-Pt. bending test. The major design goal of this new 3 Pt. bending apparatus would be to reduce the ability for a mouse femur to roll under load. This was accomplished by designing a new base for the 3-pt apparatus that inhibits the femoral head from rolling.