Parks Faculty

Scott Sell, Ph.D.,<br/>Assistant Professor

Scott Sell, Ph.D.,
Assistant Professor

Assistant Professor

Phone:
(314) 977-8286
Education:

B.S. in Biomedical Engineering
Virginia Commonwealth University

M.S. in Biomedical Engineering
Virginia Commonwealth University

Ph.D. in Biomedical Engineering
Virginia Commonwealth University

Scott A. Sell, Ph.D. is currently an Assistant Professor in Biomedical Engineering at Parks College. Dr. Sell received his education from Virginia Commonwealth University; receiving his B.S. in Biomedical Engineering in 2003, his M.S. in Biomedical Engineering in 2006, and his Ph.D. in Biomedical Engineering in 2009 working under the tutelage of Dr. Gary Bowlin.

Following his graduation, Dr. Sell completed at 3 year Polytrauma Research post-doc fellowship at the Hunter Holmes McGuire VA Medical Center in Richmond, VA.

Dr. Sell conducts research in the areas of tissue engineering and regenerative medicine, particularly focusing on the potential for electrospinning to create extracellular matrix analogue scaffolds for dermal and musculoskeletal repair. He has also done extensive research on the incorporation and controlled release of platelet-rich plasma from electrospun scaffolds.

Dr. Sell conducts research in the areas of tissue engineering and regenerative medicine, particularly focusing on the potential for electrospinning to create extracellular matrix analogue scaffolds for dermal and musculoskeletal repair. He has also done extensive research on the incorporation and controlled release of platelet-rich plasma from electrospun scaffolds.

Research Interests

Dr. Sell’s research interests include tissue engineering, regenerative medicine, electrospinning, polymeric scaffolds, dermal regeneration, and ligament repair.

Below is a list of Scott Sell’s selected publications. For more information on each publication, please visit the Parks College Publication Database.

Printed Archival Peer-Reviewed Journals
  • McClure, M.J., Garg, K., Simpson, D.G., Ryan, J.J., Sell, S.A., Bowlin, G.L., and J.J. Ericksen. “The Influence of Platelet Rich Plasma on Myogenic Differentiation.”  Journal of Tissue Engineering and Regenerative Medicine. July 2013 DOI: 10.1002/term.1755
  • Sell, S.A., Ericksen, J.J. and G.L. Bowlin. “The incorporation and controlled release of platelet-rich plasma-derived biomolecules from polymeric tissue engineering scaffolds.” Polymer International. 61 (12) 1703-1709, 2012. DOI: 10.1002/pi.4372 
  • Francis, M.P., Sachs, P.C., Madurantakam, P.A., Sell, S.A., Moghaddam, Y.M., Elmore, L.W.,  Bowlin, G.L., and S.E. Holt. “Electrospinning Adipose Tissue-derived Extracellular Matrix for Adipose Stem Cell Culture.” Journal of Biomedical Materials Research: Part A. 100 (7) 1716-1724, 2012. DOI: 10.1002/jbm.a.34126
  • McClure, M.J., Wolfe, P.S., Simpson, D.G., Sell, S.A., and G.L. Bowlin. “The use of air-flow impedance to control fiber deposition patterns during electrospinning.” Biomaterials. 33 (3) 771-779, 2012. DOI: 10.1016/j.biomaterials.2011.10.011
  • Sell, S.A., Wolfe, P.S., Ericksen, J.J., Simpson, D.G., and G.L. Bowlin. “Incorporating Platelet-Rich Plasma into Electrospun Scaffolds for Tissue Engineering Applications.” Tissue Engineering Part A., 17 (21-22), 2723-2737, 2011. DOI: 10.1089/ten.TEA.2010.0663
  • Jha, B.S., Colello, R.J., Bowman, J.R., Sell, S.A., Lee, K.D., Bigbee, J.W., Bowlin, G.L., Chow, W.N., Mathern, B.E., and D.G. Simpson. “Two pole air gap electrospinning: Fabrication of highly aligned, three dimensional scaffolds for nerve reconstruction.” Acta Biomaterialia, 7 (1), 203-215, 2011. DOI: 10.1016/j.actbio.2010.08.004
  • Sell, S.A., Ericksen, J.J., Reis, T.W., Droste, L.R., Bhuiyan, M.B.A., and D.R. Gater. “A Case Report on the Use of Sustained Release Platelet-Rich Plasma for the Treatment of Chronic Pressure Ulcers.” Journal of Spinal Cord Medicine, 34 (1), 122-127, 2011. DOI: 10.1179/107902610X12923394765616
  • Sell, S.A., McClure, M.J., Ayres, C.E., Simpson, D.G., and G.L. Bowlin. “Preliminary investigation of airgap electrospun silk fibroin-based structures for ligament analogue engineering.” Journal of Biomaterials Science: Polymer Edition, 22, 1253-1273, 2011. DOI: 10.1163/092050610X504251
  • Sell, S.A., Wolfe, P.S., Garg, K., McCool, J.M., Rodriguez, I.A., and G.L. Bowlin. “The Use of Natural Polymers in Tissue Engineering: A Focus on Electrospun Extracellular Matrix Analogues.” Polymer, 2 (4), 522-553, 2010. DOI: 10.3390/polym2040522
Online Peer-Reviewed Journals
  • Rodriguez, I.A., Sell, S.A., McCool, J.M., Saxena, G., Spence, A.J., and Bowlin, G.A. “A preliminary evaluation of lyophilized gelatin sponges enhanced with platelet-rich plasma, hydroxyapatite, and chitin whiskers for bone regeneration.” Cells. 2(2) 244-65, 2013. DOI: 10.3390/cells2020244
  • Sell, S.A., Wolfe, P.S., Spence, A.J., Rodriguez, I.A., McCool, J.M., Garg, K., Ericksen, J.J., and G.L. Bowlin. “A Preliminary Study on the Potential of Manuka Honey and Platelet-Rich Plasma in Wound Healing.” International Journal of Biomaterials. 2012, DOI: 10.1155/2012/313781 
  • Rodriguez, I.A, Madurantakam, P.A., McCool, J.M., Sell, S.A., Yang, H., Moon, P.C., and G.L. Bowlin. “Mineralization potential of electrospun PDO-hydroxyapatite-fibrinogen blended scaffolds.” International Journal of Biomaterials. 2012, DOI: 10.1155/2012/159484
  • Wolfe, P.S., Sell, S.A., Ericksen, J.J, Simpson, D.G., and G.L. Bowlin. “The Creation of Electrospun Nanofibers from Platelet-Rich Plasma.” Journal of Tissue Science & Engineering. 2:107, 2011, DOI: 10.4172/2157-7552.1000107
Conference Abstracts
  • Sell, S.A., Rodriguez, I.A., McCool, J.M., Saxena, G., Spence, A.J., and G.L. Bowlin. “A preliminary evaluation of lyophilized gelatin sponges enhanced with platelet-rich plasma, hydroxyapatite, and chitin whiskers for bone regeneration.” Poster presentation at the 17th Annual International Workshop on Tissue Engineering, Hilton Head, SC, March 19-23, 2013.
  • Sell, S.A., Wolfe, P.S., Spence, A.J., Rodriguez, I.A., McCool, J.M., Garg, K., Ericksen, J.J, and G.L. Bowlin. “The use of a combination of Manuka honey and platelet-rich plasma to stimulate dermal regeneration.” Podium presentation at the Biomedical Engineering Society (BMES), Atlanta, GA, October 24-27, 2012.
  • Sell, S.A., Wolfe, P.S., Spence, A.J., Rodriguez, I.A., McCool, J.M., Garg, K., Ericksen, J.J, and G.L. Bowlin. “The potential for accelerate wound healing with Manuka honey and platelet-rich plasma.” Poster presentation at the 16th Annual International Workshop on Tissue Engineering, Hilton Head, SC, March 14-17, 2012.
  • Sell, S.A., Wolfe, P.S., Simpson, D.G., Ericksen, J.J, and G.L. Bowlin. “Using Platelet-Rich Plasma as a Material for the Creation of Electrospun Scaffolds in Tissue Engineering.” Podium presentation at the Tissue Engineering & Regenerative Medicine International Society – North America 2011 Conference and Exposition, Houston, TX, December 11-14, 2011.
  • Sell, S.A., McClure, M.J., Wolfe, P.S., Garg, K., Ericksen, J.J, and G.L. Bowlin. “Mechanical evaluation of airgap electrospun polycaprolactone and platelet-rich plasma blends for ligament analogues.” Podium presentation at the Fourth International Conference on Mechanics of Biomaterials & Tissues. Waikoloa, Hawai’i December 11-14, 2011.
  • Sell, S.A., Ericksen, J.J., Reis, T.W., Droste, L.W., Bowlin, G.L., Bhuiyan, M.B.A., and D.R. Gater. “Sustained release platelet-rich plasma as a treatment for chronic pressure ulcers: A case report.” Podium presentation at the 15th Annual International Workshop on Tissue Engineering, Hilton Head, SC, March 16-19, 2011.
  • Sell, S.A., Wolfe, P.S., Simpson, D.G., Ericksen, J.J, and G.L. Bowlin. “The creation of electrospun nanofiber scaffolds from platelet-rich plasma.” Poster presentation at the 15th Annual International Workshop on Tissue Engineering, Hilton Head, SC, March 16-19, 2011.
  • Wijesinghe, D.S., Sell, S.A., Ericksen, J.J., and C.E. Chalfant. “Lipidomic Characterization of Platelet Rich Plasma.” Podium presentation at the 46th Annual Southeastern Regional Lipid Conference. Cashiers, NC, November 9-11, 2011.
Books
  • Wolfe, P.S., Sell, S.A., and G.L. Bowlin, “Natural and Synthetic Scaffolds.” In Tissue Engineering: From Lab to Clinic. Pallua, N; and C.V. Suscheck, Eds. Springer-Verlag, Berlin. 2011. p 41-67.
  • Garg, K., Sell, S.A., and G.L. Bowlin, “Electrospinning and its influence on the structure of polymeric nanofibers.” In Handbook of Textile Fibre Structure: Fundamentals and Manufactured Polymer Fibres. Eichhorn, S.; Hearle, J.W.S.; Jaffe, M. and T. Kikutani, Eds. Woodhead Publishing Limited, Cambridge, UK. 2009.

Tissue Engineering Scaffold Fabrication Laboratory

The focus of our lab is the fabrication and evaluation of tissue engineering scaffolds capable of replicating both the form and function of the native extracellular matrix (ECM). Through the creation of idealized tissue engineering structures, we hope to harness the body’s own reparative potential and accelerate regeneration. We are primarily interested in utilization of the electrospinning process to create nanofibrous polymeric structures that can be applied to a wide range of applications. Of principal interest to our laboratory is the fabrication of scaffolds capable of promoting wound healing and the filling of large tissue defects, as well as orthopedic applications such as bone and ligament repair. Our lab is equipped for a number of scaffold fabrication techniques, scaffold mechanical evaluation, protein analysis, and the determination of cell-scaffold interactions.