Research in Engineering and Aviation

Buoyancy-Driven Continuous SPLITT Fractionation: A New Technique for Separation of Microspheres

January 2009

Author(s): J. Storey, P. Douglas, P. M. Ligrani, and K. M. Morten,

Journal: Separation Science and Technology, Vol. 44, No. 9, pp. 1895-1922, January 2009. DOI: 10.1080/01496390902955651


A new method of Continuous Fractionation using a SPLITT cell is conceived, developed, and tested, and is demonstrated to be useful for separation of collections of particles with different sizes and densities. With this previously uninvestigated mode of operation, this is accomplished for particles by buoyancy-driven separation. Some of the capabilities of this system are illustrated by successful separations of different-sized fluorescent polymer microspheres, with different carrier densities. The resulting experimentally-measured fraction recovery variations are then in good agreement with theoretical calculation from buoyancy-driven SPLITT theory.

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